Rediscoveries are not rare in biology. A recent example is the re-birth of the "fluctuation fit" concept developed by F. B. Straub and G. Szabolcsi in the sixties of the last century, under various names, the most popular of which is the "conformational selection". This theory offers an alternative to the "induced fit" concept by Koshland for the interpretation of the mechanism of protein—ligand interactions. A central question is whether the ligand induces a conformational change (as described by the induced (...) fit model) or rather selects and stabilizes a complementary conformation from a pre-existing equilibrium of various states of the protein (according to the fluctuation fit/conformational selection model). Straub and Szabolcsi’s role and the factors hindering the spread of the fluctuation fit theory are discussed in the context of the history of the Hungarian biology in the 1950s and 1960s. (shrink)

The article offers analyses of the phenomenon of copying (plagiarism) in higher education. The analyses were based on a quantitative survey using questionnaires, conducted in 2019 at one of the Polish universities. Plagiarism is discussed here both as an element of the learning process and a subject of public practices. The article presents students’ definitions of plagiarism, their strategies for unclear or difficult situations, their experiences with plagiarism and their opinions on how serious and widespread this phenomenon is. Focusing on (...) the non-plagiarism norm, that is the rule that students are not allowed to plagiarize, and in order to redefine it we have determined two strategies adopted by students. The first is withdrawing in fear of making a mistake (omitting the norm), which means not using referencing in unclear situations, e.g. when the data about the source of information are absent. The second is reducing the scope of the norm applicability (limiting the norm), characterized by the fact that there are areas where the non-plagiarism norm must be observed more closely and those where it is not so important, e.g. respondents classify works as credit-level and diploma-level texts, as in the credit-level work they “can” sometimes plagiarize since the detection rate is poor and consequences are not severe. The presented results are particularly significant for interpreting plagiarism in an international context (no uniform definition of plagiarism) and for policies aimed at limiting the scale of the phenomenon (plagiarism detection systems 1 ). (shrink)

Nowadays financialization seems to be an inherent and obvious phenomenon and it appears to have infected all industrialized economies. Within general phenomenon of financialization, three areas should be indicated: financialization as a system of capital accumulation, financialization of business entities and financialization of every day-life. In our paper we try to investigate family businesses that are unique due to the overlap of family and business subsystems in one entity. More specifically, we undertake to find out whether intertwining of family values (...) with business objectives can influence the level of absorption of various finance instruments that are offered on nowadays financial market. Analysis revealed a few statistically significant relationships between perception of family firm objectives and absorption of basic and sophisticated finance instruments. It is the first to suggest, that family firms which are intrinsically-oriented, i.e. those more willing to keep independence or to keep long term survival, are less prone to absorb sophisticated finance instruments, e.g. private equity, venture capital, hybrid capital or they are less keen to become a public company. On the other hand, if a family firm is more oriented towards risk minimisation or keeping long term growth, then it is also more open for absorption of advanced finance instruments. (shrink)

Individualism-collectivism has emerged as one of the most important constructs to depict cultural differences and similarities. It is typical to examine individualism and collectivism through comparison between the cultures of the West and those of the East or comparison between various religious traditions, e.g. Christianity has been seen as the source of Western individualistic understanding whilst Buddhism as the source of Eastern collectivist understanding. The research presented in this paper explored the connections between individualism-collectivism and religiosity in Polish Catholic culture. (...) Although Poland is an orthodox Catholic environment, gradually intensified secularization processes have been observed there. In two separate studies we examined relationships between individualism-collectivism and religiosity defined in a traditional and secularized context. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Journal of the History of Philosophy 39.4 (2001) 467-489 [Access article in PDF] "By the Things Themselves":Eudaimonism, Direct Acquaintance, and Illumination in Augustine's De Magistro 1 Michael Mendelson 1. The Eudaimonistic Interlude It comes as a surprise. Two-thirds of the way through De Magistro, amid a torturous and at times obscure discussion of the nature of language, Augustine pauses to provide Adeodatus, his son and interlocutor, with what seems (...) a rather odd digression:...with so many detours, it's difficult to say at this point where you and I are trying to get to! Maybe you think we're playing around and diverting the mind from serious matters by some little puzzles that seem childish, or that we're pursuing some result that is only small or modest....Though we do perhaps play around, this should itself not be regarded as childish. Nor are we thinking about small and modest goods. Yet if I were to say that there is a happy and everlasting life, and I want us to be led there under the guidance of God (namely by Truth Himself) by stages that are suitable to our weak steps, I'm afraid I might seem laughable for having set out on such a long journey by considering signs rather than the things themselves that are signified. So then, you'll pardon me if I play around with you at first—not for the sake of playing around, but to exercise the mind's strength and sharpness, with which we're [End Page 467] able not only to withstand but also to love the heat and light of that region where the happy life is. 2One is left wondering—if one pauses long enough to wonder at all—what exactly the preceding tightly woven and technical discussion of signification has to do with the "heat" (calor) and the "light" (lux) of the "region" (regio) where the "happy life" (beata vita) is to be found. Indeed, even the passage itself acknowledges the ostensible obliqueness of the connection without doing very much to highlight its nature.It is not surprising that readers of De Magistro often overlook this eudaimonistic interlude in favor of the more prominent and arresting difficulties with which the text confronts us. There is, after all, the somewhat awkward view of language which underlies the entire discussion, and there is also what seems to be the abrupt and jarring reversal of positions that occurs near the very end of the text. Perhaps most notorious of all, there is the famous theory of "divine illumination" with which the dialogue concludes. It is worth noting, however, that as odd and as digressive as this eudaimonistic interlude may strike the present-day reader, it does not seem to strike Adeodatus as at all odd, nor does it seem out of keeping with the eudaimonistic emphasis that is such a prominent feature of Augustine's other works from roughly the same period. 3 Indeed, our passage, although easily swept aside and passed over, can do much to provide a unifying strand which ties our difficulties together; it is, indeed, a helpful prism through which we can view those difficulties in a new light. [End Page 468] 2. Some Initial Darkness And the difficulties are indeed quite real. To begin with, there is the awkward view of language that underlies the entire discussion. "Words" (verba) are "signs" (signa) (DM 2.3), and there is a fundamental distinction between a "sign" and "signifiables" (significabilia) which are signified by signs (DM 4.8). Language, on this account, is fundamentally instrumental (see, e.g., DM 9.25), for each word is a means by which one attempts to draw attention to that which the word, qua sign, somehow signifies. As Wittgenstein says in his famous gloss on Confessions I.8, In this picture of language we find the roots of the following idea, E.g. Every word has a meaning. The meaning is correlated with the word. It is the object for which the word stands... (shrink)

John Buridan was a fourteenth-century philosopher who enjoyed an enormous reputation for about two hundred years, was then totally neglected, and is now being 'rediscovered' through his relevance to contemporary work in philosophical logic. The final chapter of Buridan's Sophismata deals with problems about self-reference, and in particular with the semantic paradoxes. He offers his own distinctive solution to the well-known 'Liar Paradox' and introduces a number of other paradoxes that will be unfamiliar to most logicians. Buridan also moves on (...) from these problems to more general questions about the nature of propositions, the criteria of their truth and falsity and the concepts of validity and knowledge. This edition of that chapter is intended to make Buridan's ideas and arguments accessible to a wider range of readers. The volume should interest many philosophers, linguists and logicians, who are increasingly finding in medieval work striking anticipations of their own concerns. (shrink)

Response to commentaries on keynote article.

According to the prevailing sentiment, changing the past is logically impossible. The prevailing sentiment is wrong. In this paper, I argue that the claim that changing the past entails a contradiction ultimately rests upon an empirical assumption, and so the conclusion that changing the past is logically impossible is to be resisted. I then present and discuss a model of time which drops the empirical assumption and coherently models changing the past. Finally, I defend the model, and changing the past, (...) against objections. (shrink)

This original and lively book uses texts from ancient medicine, epic, lyric, tragedy, historiography, philosophy, and religion to explore the influence of Greek ideas on health and disease on Greek thought. Fundamental issues are deeply implicated: causation and responsibility, purification and pollution, the mind-body relationship and gender differences, authority and the expert, reality and appearances, good government, and good and evil themselves.

In this paper I will argue that the latter group [of Non-Humeans] is correct. My argument focuses on practical deliberation and has two parts. I will discuss two different problems that arise for the Humean Theory and suggest that while taken individually each problem appears to have a solution, for each problem the solution Humeans offer precludes solving the other problem. I will suggest that to see these difficulties we must take seriously the thought that we can only understand an (...) agent’s reasons for her action by looking at her actual or possible practical deliberation. (shrink)

In ‘Wittgenstein on Language and Rules’, Professor N. Malcolm took us to task for misinterpreting Wittgenstein's arguments on the relationship between the concept of following a rule and the concept of community agreement on what counts as following a given rule. Not that we denied that there are any grammatical connections between these concepts. On the contrary, we emphasized that a rule and an act in accord with it make contact in language. Moreover we argued that agreement in judgments and (...) in definitions is indeed necessary for a shared language. But we denied that the concept of a language is so tightly interwoven with the concept of a community of speakers as to preclude its applicabilty to someone whose use of signs is not shared by others. Malcolm holds that ‘This is an unwitting reduction of Wittgenstein's originality. That human agreement is necessary for “shared” language is not so striking a thought as that it is essential for language simpliciter.’ Though less striking, we believe that it has the merit of being a true thought. We shall once more try to show both that it is correct, and that it is a correct account of Wittgenstein's arguments. (shrink)

Dealing with the nature of historical knowledge, this book is concerned with both philosophical and historical questions. It involves considerations as various as statistical hypothesis testing, componential analysis and the problem of the Synoptic Gospels. --.

The purpose of this note is to acknowledge a gap in a previous paper, "The complexity of revision," and to provide a corrected version of the argument.

"This book represents a continuation of the research project in philosophy of language and semantics represented in the journal "Protosociology" at the J. W. ...

The study of continuous group actions is ubiquitous in mathematics, and perhaps the most general kinds of actions for which we can hope to prove theorems in just ZFC are those where a Polish group acts on a Polish space.For this general class we can find works such as [29] that build on ideas from ergodic theory and examine actions of locally compact groups in both the measure theoretic and topological contexts. On the other hand a text in model theory, (...) such as [12], will typically consider issues bearing on the actions by the symmetric group of all permutations of the integers. More generally [1] shows that the orbit equivalence relations induced by closed subgroups of the infinite symmetric group can be reduced to the isomorphism relation on corresponding classes of countable models.This paper considers a third category formed by the continuous actions of separable Banach spaces on Polish spaces. These examples cannot be subsumed under the two earlier headings, and it is known from [10] that theBorel cardinalitiesof the quotient spaces that arise from such actions are incomparable with the equivalence relations induced by the symmetric group or any locally compact Polish group action.One of the first things to be addressed concerns the complexity of these equivalence relations. This question forappears in [1]. (shrink)